Literature summary extracted from

Ma , C.; Yang, Y.; Xu, L.; Tu, W.; Chen, F.; Wang, J.
Rce1 suppresses invasion and metastasis of hepatocellular carcinoma via epithelial-mesenchymal transition induced by the TGF-beta1/H-Ras signaling pathway (2020), J. Cell. Physiol., 235, 2506-2520 .

Application

EC Number	Application	Comment	Organism
3.4.99.B1	medicine	expression of Rce1 is significantly decreased in hepatocellular carcinoma compared with noncancerous tissues, while H-Ras expression is increased in the tumor. The expression of both is a close association with the differentiation and tumor-node-metastasis stage of the tumor. Rce1 is an independent prognostic indicator. Lower expression of Rce1 facilitates epithelial-mesenchymalctransition and promotes the invasion and metastasis of hepatocellular carcinoma	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.99.B1	Homo sapiens	Q9Y256	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.99.B1	hepatoma cell	-	Homo sapiens	-
3.4.99.B1	liver	-	Homo sapiens	-

General Information

EC Number	General Information	Comment	Organism
3.4.99.B1	physiological function	Rce1 can bind with farnesyltransferase beta	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)